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1

Chemical Genetic Blockade of Transformation Reveals Dependence on Aberrant Oncogenic Signaling

Qi-Wen Fan, Chao Zhang, Kevan M. Shokat, William A. Weiss

Journal:

Current Biology

Year:

2002

Language:

english

File:

PDF, 597 KB

english, 2002

2

Nitrate-induced elevations in circulating sex steroid concentrations in female Siberian sturgeon (Acipenser baeri) in commercial aquaculture

Heather J. Hamlin, Brandon C. Moore, Thea M. Edwards, Iskande L.V. Larkin, Ashley Boggs, William J. High, Kevan L. Main, Louis J. Guillette Jr.

Journal:

Year:

2008

Language:

english

File:

PDF, 546 KB

english, 2008

3

from angle-resolved photoemission

Wehner, P. S., Williams, R. S., Kevan, S. D., Denley, D., Shirley, D. A.

Journal:

Physical Review B

Year:

1979

Language:

english

File:

PDF, 592 KB

english, 1979

4

Angle-resolved photoemission studies of the valence-band structure of stepped crystal surfaces: Cu(S)-[3(111) × (100)]

Davis, R. F., Williams, R. S., Kevan, S. D., Wehner, P. S., Shirley, D. A.

Journal:

Physical Review B

Year:

1985

Language:

english

File:

PDF, 543 KB

english, 1985

5

Two Analytical Methods for the Measurement of 2,4-D in Oranges: an ELISA Screening Procedure and a GC-MS Confirmatory Procedure

Williams, Kevan J., James, C. Richard, Thorpe, Stephen A., Reynolds, Stewart L.

Journal:

Pesticide Science

Year:

1997

Language:

english

File:

PDF, 233 KB

english, 1997

6

A microbore high performance liquid chromatography/electrospray ionization mass spectrometry method for the determination of the phytoestrogens genistein and daidzein in comminuted baby foods and soya flour

Karen A. Barnes, Rosemary A. Smith, Kevan Williams, Andrew P. Damant, Martin J. Shepherd

Journal:

Rapid Communications in Mass Spectrometry

Year:

1998

Language:

english

File:

PDF, 307 KB

english, 1998

7

Discovery of Dual Inhibitors of the Immune Cell PI3Ks p110δ and p110γ: a Prototype for New Anti-inflammatory Drugs

Olusegun Williams, Benjamin T. Houseman, Eric J. Kunkel, Brian Aizenstein, Randy Hoffman, Zachary A. Knight, Kevan M. Shokat

Journal:

Chemistry & Biology

Year:

2010

Language:

english

File:

PDF, 2.42 MB

english, 2010

8

The effect of N-acyl substituents on the stability of monocyclic β-lactam inhibitors of human leukocyte elastase

William K. Hagmann, Kevan R. Thompson, Shrenik K. Shah, Paul E. Finke, Bonnie M. Ashe, Hazel Weston, Alan L. Maycock, James B. Doherty

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1992

Language:

english

File:

PDF, 282 KB

english, 1992

9

Rational design of high affinity tachykinin NK1 receptor antagonists

Steven Boyle, Steven Guard, Michael Higginbottom, David C. Horwell, William Howson, Alexander T. McKnight, Kevan Martin, Martyn C. Pritchard, John O'Toole, Jenny Raphy, David C. Rees, Edward Roberts,

Journal:

Bioorganic & Medicinal Chemistry

Year:

1994

Language:

english

File:

PDF, 2.14 MB

english, 1994

10

Adsorbate sensitivity enhancement in photoemission: CO on Pd

P.S. Wehner, S.D. Kevan, R.S. Williams, R.F. Davis, D.A. Shirley

Journal:

Chemical Physics Letters

Year:

1978

Language:

english

File:

PDF, 389 KB

english, 1978

11

Prevention of human leukocyte elastase-mediated lung damage by 3-alkyl-4-azetidinones

William K. Hagmann, Shrenik K. Shah, Conrad P. Dorn, Laura A. O'Grady, Jeffrey J. Hale, Pau.E. Finke, Kevan R. Thompson, Karen a. Brause, Bonnie M. Ash, Hazel Weston, M.Ellen Dahlgren, Alan L. Maycock

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

1991

Language:

english

File:

PDF, 484 KB

english, 1991

12

A Raf-induced allosteric transition of KSR stimulates phosphorylation of MEK

Brennan, Damian F., Dar, Arvin C., Hertz, Nicholas T., Chao, William C. H., Burlingame, Alma L., Shokat, Kevan M., Barford, David

Journal:

Year:

2011

Language:

english

File:

PDF, 1.20 MB

english, 2011

13

Targeted polypharmacology: discovery of dual inhibitors of tyrosine and phosphoinositide kinases

Apsel, Beth, Blair, Jimmy A, Gonzalez, Beatriz, Nazif, Tamim M, Feldman, Morri E, Aizenstein, Brian, Hoffman, Randy, Williams, Roger L, Shokat, Kevan M, Knight, Zachary A

Journal:

Nature Chemical Biology

Year:

2008

Language:

english

File:

PDF, 794 KB

english, 2008

14

Recognizing and exploiting differences between RNAi and small-molecule inhibitors

Weiss, William A, Taylor, Stephen S, Shokat, Kevan M

Journal:

Nature Chemical Biology

Year:

2007

Language:

english

File:

PDF, 2.07 MB

english, 2007

15

Structure-guided development of affinity probes for tyrosine kinases using chemical genetics

Blair, Jimmy A, Rauh, Daniel, Kung, Charles, Yun, Cai-Hong, Fan, Qi-Wen, Rode, Haridas, Zhang, Chao, Eck, Michael J, Weiss, William A, Shokat, Kevan M

Journal:

Nature Chemical Biology

Year:

2007

Language:

english

File:

PDF, 1.82 MB

english, 2007

16

Anti-CD3 Monoclonal Antibody in New-Onset Type 1 Diabetes Mellitus

Herold, Kevan C., Hagopian, William, Auger, Julie A., Poumian-Ruiz, Ena, Taylor, Lesley, Donaldson, David, Gitelman, Stephen E., Harlan, David M., Xu, Danlin, Zivin, Robert A.

Journal:

Boston Medical and Surgical Journal

Year:

2002

Language:

english

File:

PDF, 110 KB

english, 2002

17

The In Vivo Response of Stem and Other Undifferentiated Spermatogonia to the Reversible Inhibition of Glial Cell Line-Derived Neurotrophic Factor Signaling in the Adult

Joseph Savitt, Dolly Singh, Chao Zhang, Liang-Chin Chen, Janet Folmer, Kevan M. Shokat, William W. Wright

Journal:

Year:

2012

Language:

english

File:

PDF, 1.34 MB

english, 2012

18

A dual PI3 kinase/mTOR inhibitor reveals emergent efficacy in glioma

Qi-Wen Fan, Zachary A. Knight, David D. Goldenberg, Wei Yu, Keith E. Mostov, David Stokoe, Kevan M. Shokat, William A. Weiss

Journal:

Year:

2006

Language:

english

File:

PDF, 515 KB

english, 2006

19

Treatment of patients with new onset Type 1 diabetes with a single course of anti-CD3 mAb teplizumab preserves insulin production for up to 5 years

Kevan C. Herold, Stephen Gitelman, Carla Greenbaum, Jennifer Puck, William Hagopian, Peter Gottlieb, Peter Sayre, Peter Bianchine, Emelita Wong, Vicki Seyfert-Margolis, Kasia Bourcier, Jeffrey A. Blue

Journal:

Clinical Immunology

Year:

2009

Language:

english

File:

PDF, 449 KB

english, 2009

20

Skeletal fluorosis and instant tea

Michael P. Whyte, Kevan Essmyer, Francis H. Gannon, William R. Reinus

Journal:

The American Journal of Medicine

Year:

2005

Language:

english

File:

PDF, 140 KB

english, 2005

21

The F Box Protein Dsg1/Mdm30 Is a Transcriptional Coactivator that Stimulates Gal4 Turnover and Cotranscriptional mRNA Processing

Masafumi Muratani, Charles Kung, Kevan M. Shokat, William P. Tansey

Journal:

Year:

2005

Language:

english

File:

PDF, 621 KB

english, 2005

22

A Chemical-Genetic Strategy Implicates Myosin-1c in Adaptation by Hair Cells

Jeffrey R. Holt, Susan K.H. Gillespie, D.William Provance Jr., Kavita Shah, Kevan M. Shokat, David P. Corey, John A. Mercer, Peter G. Gillespie

Journal:

Year:

2002

Language:

english

File:

PDF, 460 KB

english, 2002

23

Performance of Para-Pak™ Ultra ECOFIX™ compared with Para-Pak™ Ultra formalin/mercuric chloride-based polyvinyl alcohol for concentration and permanent stained smears of stool parasites

Daniel P Fedorko, Esther C Williams, Nancy A Nelson, Tangela D Mazyck, Kevan L Hanson, Charles P Cartwright

Journal:

Diagnostic Microbiology and Infectious Disease

Year:

2000

Language:

english

File:

PDF, 48 KB

english, 2000

24

Nrf2 protects human alveolar epithelial cells against injury induced by influenza A virus

Beata Kosmider, Elise M Messier, William J Janssen, Piruz Nahreini, Jieru Wang, Kevan L Hartshorn, Robert J Mason

Journal:

Respiratory Research

Year:

2012

Language:

english

File:

PDF, 1.13 MB

english, 2012

25

Tuning a Three-Component Reaction For Trapping Kinase Substrate Complexes

Statsuk, Alexander V., Maly, Dustin J., Seeliger, Markus A., Fabian, Miles A., Biggs, William H., Lockhart, David J., Zarrinkar, Patrick P., Kuriyan, John, Shokat, Kevan M.

Journal:

Journal of the American Chemical Society

Year:

2008

Language:

english

File:

PDF, 1.05 MB

english, 2008

26

An Experimental Assessment of Recent Professional Developments in Nonstatistical Audit Sampling Guidance

Messier, William F., Kachelmeier, Steven J., Jensen, Kevan L.

Journal:

Auditing A Journal of Practice & Theory

Year:

2001

Language:

english

File:

PDF, 128 KB

english, 2001

27

128 Evaluation of Genetic and Microbial Determinants of Intestinal Permeability in Healthy First Degree Relatives of Crohn's Disease

Kevans, David, Turpin, Williams, Madsen, Karen, Meddings, Jon, Moreno-Hagelsieb, Gabriel, Xu, Wei, Silverberg, Mark S., Paterson, Andrew D., Croitoru, Ken

Journal:

Gastroenterology

Year:

2014

Language:

english

File:

PDF, 65 KB

english, 2014

28

Tu1757 Intestinal Microbiota Is a Heritable Trait in Healthy Subjects

Turpin, Williams, Silverberg, Mark S., Moreno-Hagelsieb, Gabriel, Kevans, David, Xu, Wei, Onay, Venus, Croitoru, Ken, Paterson, Andrew D.

Journal:

Gastroenterology

Year:

2014

Language:

english

File:

PDF, 204 KB

english, 2014

29

Vertebrate versus invertebrate neural circuits

Katz, Paul, Grillner, Sten, Wilson, Rachel, Borst, Alexander, Greenspan, Ralph, Buzsáki, György, Martin, Kevan, Marder, Eve, Kristan, William, Friedrich, Rainer, Chklovskii, Dmitri “Mitya”

Journal:

Current Biology

Year:

2013

Language:

english

File:

PDF, 243 KB

english, 2013

30

Plant Antimutagenic Agents 7. Structure and Antimutagenic Properties of Cymobarbatol and 4-Isocymbarbatol, New Cymopols from Green Alga (Cymopolia barbata)

Wall, Monroe E., Wani, Mansukh C., Manikumar, Govindarajan, Taylor, Harold, Hughes, Thomas J., Gaetano, Kevan, Gerwick, William H., McPhail, Andrew T., McPhail, Donald R.

Journal:

Journal of Natural Products

Year:

1989

Language:

english

File:

PDF, 532 KB

english, 1989

31

Identification of Novel Metabolites of Butadiene Monoepoxide in Rats and Mice

Richardson, Kevan A., Peters, Melanie M. C. G., Megens, René H. J. J. J., van Elburg, Paul A., Golding, Bernard T., Boogaard, Peter J., Watson, William P., van Sittert, Nico J.

Journal:

Chemical Research in Toxicology

Year:

1998

Language:

english

File:

PDF, 166 KB

english, 1998

32

General discussion

Lunell, S., Iwasaki, M., Sevilla, M., Kevan, L., Klassen, N., Symons, M. C. R., Toriyama, K., Williams, F., Wasielewski, M. R., Siebrand, W., Cox, S. F. J., Roduner, E., Kemp, T. J., Davies, A. G., Al

Journal:

Faraday Discussions of the Chemical Society

Year:

1984

Language:

english

File:

PDF, 1.99 MB

english, 1984

33

[IEEE 2009 Second International Conference in Visualisation (VIZ) - Barcelona, Spain (2009.07.15-2009.07.17)] 2009 Second International Conference in Visualisation - 3D ePortfolios: Challenges and Opportunities for the Display of Interactive Models of Building Designs

Hetherington, Robina, Williams, Kevan

Year:

2009

Language:

english

File:

PDF, 1.28 MB

english, 2009

34

Southern Blot Analysis of Cerebrospinal Fluid Lymphocytosis

Williams, Michael E., Grosh, William W., VanLandingham, Kevan E., Innes, Donald J.

Journal:

Cancer Investigation

Year:

1990

Language:

english

File:

PDF, 229 KB

english, 1990

35

Identification of a Surface State on the (111) Terraces of Stepped Cu(211).

Williams, R. S., Wehner, P. S., Kevan, S. D., Davis, R. F., Shirley, D. A.

Journal:

Physical Review Letters

Year:

1978

Language:

english

File:

PDF, 90 KB

english, 1978

36

PTEN expression is consistent in colorectal cancer primaries and metastases and associates with patient survival

Atreya, Chloe E., Sangale, Zaina, Xu, Nafei, Matli, Mary R., Tikishvili, Eliso, Welbourn, William, Stone, Steven, Shokat, Kevan M., Warren, Robert S.

Journal:

Cancer Medicine

Year:

2013

Language:

english

File:

PDF, 2.50 MB

english, 2013

37

Early pancreas allograft thrombosis

Ramessur Chandran, Sharmila, Kanellis, John, Polkinghorne, Kevan R., Saunder, Alan C., Mulley, William R.

Journal:

Clinical Transplantation

Year:

2013

Language:

english

File:

PDF, 106 KB

english, 2013

38

Yale Center for Clinical Investigation: Leveraging Industry Partnerships and Research Cores

Sherwin, Robert, Slayman, Carolyn, Rockwell, Sara, Herold, Kevan, Williams, Kenneth, Carson, Richard, Mane, Shrikant, Seow, Helen, Max, Jill, Johnson, Tesheia

Journal:

Clinical and Translational Science

Year:

2012

Language:

english

File:

PDF, 497 KB

english, 2012

39

Aging effects in bulk and fiber TlBr-TlI

Wysocki, Joseph A., Wilson, Robert G., Standlee, Arlie G., Pastor, Antonio C., Schwartz, Robert N., Williams, Arthur R., Lei, Guan-Dao, Kevan, Larry

Journal:

Journal of Applied Physics

Year:

1988

Language:

english

File:

PDF, 1014 KB

english, 1988

40

Identification of Chemisorption Levels on Iridium by Field-Emission Spectroscopy

Williams, R. S., Wehner, P. S., Kevan, S. D., Davis, R. F., Shirley, D. A.

Journal:

Physical Review Letters

Year:

1978

Language:

english

File:

PDF, 768 KB

english, 1978

41

Derivation of Non-Lymphopenic BB Rats with an Intercross Breeding

Herold, Kevan C., Kastern, William, Markholst, Helle, Lernmarkw, Ake, Andreason, Bodil E.

Journal:

Year:

1989

Language:

english

File:

PDF, 720 KB

english, 1989

42

Determinants of Intestinal Permeability in Healthy First-Degree Relatives of Individuals with Crohnʼs Disease

Kevans, David, Turpin, Williams, Madsen, Karen, Meddings, Jon, Shestopaloff, Konstantin, Xu, Wei, Moreno-Hagelsieb, Gabriel, Griffiths, Anne, Silverberg, Mark S., Paterson, Andrew, Croitoru, Kenneth

Journal:

Inflammatory Bowel Diseases

Year:

2015

Language:

english

File:

PDF, 488 KB

english, 2015

43

Diagnostic Performance of Rapid Diagnostic Tests versus Blood Smears for Malaria in US Clinical Practice

Stauffer, William M., Cartwright, Charles P., Olson, Douglas A., Juni, Billie Anne, Taylor, Charlotte M., Bowers, Susan H., Hanson, Kevan L., Rosenblatt, Jon E., Boulware, David R.

Journal:

Clinical Infectious Diseases

Year:

2009

Language:

english

File:

PDF, 293 KB

english, 2009

44

The Development of Public Libraries in the United States, 1870–1930: A Quantitative Assessment

Kevane, Michael, Sundstrom, William A.

Journal:

Information & Culture

Year:

2014

Language:

english

File:

PDF, 16.00 MB

english, 2014

45

Pixelated Detector With Photon Address Event Driven Time Stamping and Correlation

Williams, George M., Rhee, Jehyuk, Lee, Adam, Kevan, Stephen D.

Journal:

IEEE Transactions on Nuclear Science

Year:

2014

Language:

english

File:

PDF, 1.78 MB

english, 2014

46

Mycophenolate and lower graft function reduce the seroresponse of kidney transplant recipients to pandemic H1N1 vaccination

Mulley, William R, Visvanathan, Kumar, Hurt, Aeron C, Brown, Fiona G, Polkinghorne, Kevan R, Mastorakos, Tasoula, Lewicki, Michelle C, Stuart, Rhonda L, Tan, Sven-Jean, Chean, Roy, Kerr, Peter G, Kane

Journal:

Kidney International

Year:

2012

Language:

english

File:

PDF, 264 KB

english, 2012

47

Chemical, Biochemical, Pharmacokinetic, and Biological Properties of L-680, 833: A Potent, Orally Active Monocyclic β-Lactam Inhibitor of Human Polymorphonuclear Leukocyte Elastase

James B. Doherty, Shrenik K. Shah, Paul E. Finke, Conrad P. Dorn, Jr., William K. Hagmann, Jeffrey J. Hale, Amy L. Kissinger, Kevan R. Thompson, karen Brause, Gilbert O. Chandler, Wilson B. Knight, Al

Journal:

Proceedings of the National Academy of Sciences

Year:

1993

Language:

english

File:

PDF, 923 KB

english, 1993

48

Using hydrogen deuterium exchange mass spectrometry to engineer optimized constructs for crystallization of protein complexes: Case study of PI4KIIIβ with Rab11

Fowler, Melissa L., McPhail, Jacob A., Jenkins, Meredith L., Masson, Glenn R., Rutaganira, Florentine U., Shokat, Kevan M., Williams, Roger L., Burke, John E.

Journal:

Protein Science

Year:

2016

Language:

english

File:

PDF, 1.09 MB

english, 2016

49

A chemical screen in diverse breast cancer cell lines reveals genetic enhancers and suppressors of sensitivity to PI3K isoform-selective inhibition

Torbett, Neil E., Luna-Moran, Antonio, Knight, Zachary A., Houk, Andrew, Moasser, Mark, Weiss, William, Shokat, Kevan M., Stokoe, David

Journal:

Biochemical Journal

Year:

2008

Language:

english

File:

PDF, 1.52 MB

english, 2008

50

ATPS-94THIRD GENERATION mTOR INHIBITORS IN GLIOBLASTOMA

Fan, QiWen, Wong, Robyn, Novotny, Chris, Okaniwa, Masanori, Nicolaides, Theodore, Shokat, Kevan, Weiss, William

Journal:

Year:

2015

Language:

english

File:

PDF, 23 KB

english, 2015